Evaluation of Vitamin D3 and Vitamin E levels in Rheumatoid Arthritis Patients

Abstract

Rheumatoid Arthritis (RA) is characterized by both systemic and local inflammation. It is considered to be among the most common systemic inflammatory illnesses, which include synovial swelling that can lead to joint degeneration and extra-articular complaints if not solved. Vitamin D may be linked to an increased likelihood of getting rheumatoid arthritis (RA), as well as symptoms in individuals. People with RA had considerably greater symptoms of drying (ocular, cutaneous, and mouth), which might have been due to subsequent Rheumatoid Arthritis (RA) itself.

The study sought to investigate vitamin D3 and E levels in RA individuals as well as determine their relationship to disease activity. A doctor working at Baqubah medical center and a private practice reported 100 cases (80 individuals infected with rheumatoid arthritis and 20 controls). From each scenario, samples of blood were taken.

The findings regarding determining vitamin D and E levels significantly dissimilar. The Patients' sample registered arithmetic mean levels for vitamins D3 (21.18 ± 1.10), whereas the control sample had a mathematical mean (24.35 ± 2.01).

There was no substantial difference between the two groups. In terms of vitamin E, the sick group had a lower arithmetic mean (23.52±1.25) compared to the control group (30.54±2.28), indicating a significant distinction within the groups.

Patients with RA had significantly lower vitamin E and D levels, which suggests that their antioxidant defense systems are weaker and oxidative stress is higher.